Contact a Case Manager for assistance

at 1-866-ACTELION
(1-866-228-3546).

Mon-Fri, 8 am-8 pm ET.

UPTRAVI® (selexipag) Patient Resources

The following resources are designed to help you as you start treatment with UPTRAVI. You will also find common questions and answers about Actelion Pathways® and UPTRAVI.

There are many resources you can download.

UPTRAVI Patient BrochurePrescribing Information A brochure that provides education about PAH and treatment with UPTRAVI.
Help to Get You Started Patient Pamphlet An outline of the support and services available once you have been prescribed UPTRAVI.
Titration GuidePrescribing Information A guide that highlights the important steps and information about titration with UPTRAVI.

Remember, your healthcare team should always be your first point of contact when you have questions about your health and your treatment.

Frequently Asked Questions (FAQs)

Actelion Pathways provides you with support and services, including benefits verification.

Actelion provides a wide range of support and services through Actelion Pathways. If you choose to enroll, your Actelion Pathways Case Manager will call you to:

  • Help answer your questions about filling your prescription
  • Coordinate with your healthcare provider and specialty pharmacy to help get you your medicine
  • Inform you of financial assistance programs based on your eligibility

The assistance of Actelion Pathways and Case Managers is available at no cost to patients taking UPTRAVI.

Enroll today. Call an Actelion Pathways Case Manager at 1-866-ACTELION (1-866-228-3546), Mon-Fri, 8 am-8 pm ET.

Spanish speakers and other language services are available.

Your Actelion Pathways Case Manager may be able to help. Call 1-866-ACTELION (1-866-228-3546), Mon-Fri, 8 am-8 pm ET to speak to an Actelion Pathways Case Manager.

Spanish speakers and other language services are available.

To learn about the basic steps to getting an Actelion medicine, download and review Steps to Getting Your Medicine.

Actelion medicines are available by mail from a specialty pharmacy. This is a pharmacy that can ship certain medicines directly to your home.

Learn about Working With a Specialty Pharmacy.

A specialty pharmacy will ship UPTRAVI to your home and may offer additional support services.

Either CVS Specialty or Accredo specialty pharmacy will call you to discuss financial responsibilities and shipment information.

You or your healthcare provider may have chosen additional support services such as an in-home nurse visit. Your specialty pharmacy will help you to schedule this.

Calls may come from a number you do not recognize. If you miss the call, try to call back as soon as possible to make sure your UPTRAVI shipment is not delayed.

Your insurance provider will need to gather information about your condition and your treatment before covering UPTRAVI. Sometimes, all their questions are answered at the time of prescription. They may also need more information, including:

  • Diagnostic test results, such as the numbers from your right heart catheterization (RHC)
  • Additional test results, including acute vasoreactivity testing or 6-minute walk distance (6MWD)
  • Details on past treatments you and your healthcare team have tried
  • Information missing from your prescription forms

You may receive additional optional support services, such as an in-home nurse visit before starting UPTRAVI and specialty pharmacy clinician calls during dose changes.

There are several options available from Actelion that can help you pay for UPTRAVI, if you are eligible.

Commercially insured
If you receive insurance through your employer or purchase it privately
Actelion Oral PAH Therapy Co-Pay Program* A savings program that lets eligible patients pay $5 per prescription fill per product. Contact an Actelion Pathways Case Manager for more information. Call 1-866-ACTELION (1-866-228-3546) Mon-Fri, 8 am-8 pm ET.*
Government insured
If you receive your medication through Medicare or other government-funded plans
Independent foundations There may be support available from independent third-party patient support foundations. An Actelion Pathways Case Manager can provide general information about resources.
Uninsured or underinsured
If you are uninsured or the cost of your medicine is covered by insurance, but you are unable to afford the out-of-pocket costs
Patient Assistance Program (PAP) A yearly program that helps you receive medicine at no cost. Contact an Actelion Pathways Case Manager to learn more.
Bridge Program (temporary patient assistance program) Offers 90 days of free drug coverage for patients when coverage is not immediately available (e.g., waiting for coverage to start, waiting for approval of prior authorization appeal, etc). Contact an Actelion Pathways Case Manager to learn more.

*Applies to patients who have provided consent to services offered by Actelion Pathways. The Actelion Oral PAH Therapy Co-Pay Program is only available for residents of the US and Puerto Rico who are 18 or older and have commercial health insurance with co-pay/co-insurance exceeding $5 per prescription fill per product. Patients ineligible for the Actelion Oral PAH Therapy Co-Pay Program include those enrolled in Medicare, Medicaid, VA/DoD (Tricare), the Indian Health Service, or any other federal- or state-funded healthcare program, or where prohibited by law. The Actelion Oral PAH Therapy Co-Pay Program is not prescription drug coverage or insurance. Actelion reserves the right to terminate or modify this program at any time or without notice. Other terms and conditions apply.

Find out more in Finding Support and Financial Assistance and by speaking with a Case Manager.

There are independent organizations that can provide you with additional support and information:

  • The Pulmonary Hypertension Association is dedicated to increasing awareness and advocacy by providing information about PAH to both physicians and patients. Visit them online
  • The Scleroderma Foundation offers a site for scleroderma patients, caregivers, and family members—dedicated to support, education, and research. Visit their website to learn more

Still have questions?
If you have been prescribed an Actelion medicine and have questions, call 1-866-ACTELION (1-866-228-3546). An Actelion Pathways Case Manager is available to assist you Mon-Fri, 8 am-8 pm ET. Spanish speakers and other language services are available.

IMPORTANT SAFETY INFORMATION

What is the most important information about UPTRAVI?

Who should not take UPTRAVI?

  • Do not take UPTRAVI if you take gemfibrozil because this medicine may affect how UPTRAVI works and cause side effects

What should I tell my doctor before taking UPTRAVI?

Tell your doctor if you:

  • Have liver problems
  • Have narrowing of the pulmonary veins (veins in your lungs). This is called pulmonary veno-occlusive disease (PVOD)
  • Are pregnant or plan to become pregnant. It is not known if UPTRAVI will harm your unborn baby
  • Are breastfeeding or plan to breastfeed. It is not known if UPTRAVI passes into your breast milk. You and your doctor should decide if you will take UPTRAVI or breastfeed. You should not do both.
  • Have any other medical conditions
  • Are taking any other prescription or over-the-counter medicines, vitamins, or herbal supplements
See More

What is UPTRAVI?

UPTRAVI (selexipag) is a prescription medicine used to treat pulmonary arterial hypertension (PAH, WHO Group 1), which is high blood pressure in the arteries of your lungs.

IMPORTANT SAFETY INFORMATION

What is the most important information about UPTRAVI?

Who should not take UPTRAVI?

  • Do not take UPTRAVI if you take gemfibrozil because this medicine may affect how UPTRAVI works and cause side effects

What should I tell my doctor before taking UPTRAVI?

Tell your doctor if you:

  • Have liver problems
  • Have narrowing of the pulmonary veins (veins in your lungs). This is called pulmonary veno-occlusive disease (PVOD)
  • Are pregnant or plan to become pregnant. It is not known if UPTRAVI will harm your unborn baby
  • Are breastfeeding or plan to breastfeed. It is not known if UPTRAVI passes into your breast milk. You and your doctor should decide if you will take UPTRAVI or breastfeed. You should not do both.
  • Have any other medical conditions
  • Are taking any other prescription or over-the-counter medicines, vitamins, or herbal supplements
See More

What is UPTRAVI?

UPTRAVI (selexipag) is a prescription medicine used to treat pulmonary arterial hypertension (PAH, WHO Group 1), which is high blood pressure in the arteries of your lungs.

UPTRAVI can help delay (slow down) the progression of your disease and lower your risk of being hospitalized for PAH.

It is not known if UPTRAVI is safe and effective in children.


What are the possible side effects of UPTRAVI?

The most common side effects are:

  • Headache
  • Diarrhea
  • Jaw pain
  • Nausea
  • Muscle pain
  • Vomiting
  • Pain in arms or legs
  • Temporary reddening of the skin (flushing)
  • Joint pain
  • Low red blood cell count
  • Less appetite than usual
  • Rash

Talk to your doctor if you have a side effect that bothers you or does not go away. These are not all the possible side effects of UPTRAVI. For more information, ask your doctor or pharmacist.

You may report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Keep UPTRAVI and all other medicines away from children.

What other medicines might interact with UPTRAVI?

  • UPTRAVI and other medicines may affect each other, causing side effects. Tell your doctor about all the medicines you are taking. Do not start any new medicine until you check with your doctor

How should I take UPTRAVI?

  • Take UPTRAVI exactly as your doctor tells you to take it. Usually, your doctor will have you take UPTRAVI twice a day. Taking UPTRAVI with food may help you tolerate UPTRAVI better
  • Swallow UPTRAVI tablets whole. Do not split, crush, or chew tablets
  • Tell your doctor if you have any form of liver disease. Your doctor may need to change your dose of UPTRAVI
  • UPTRAVI is measured in micrograms (mcg). Tablets come in the following strengths: 200, 400, 600, 800, 1000, 1200, 1400, and 1600 mcg

Please see full Prescribing Information and Patient Product Information for UPTRAVI.