Contact a Case Manager for assistance

at 1-866-ACTELION
(1-866-228-3546).

Mon-Fri, 8 am-8 pm ET.

Working With a Specialty Pharmacy

We understand that it is important for you to get your medicine in a timely manner. After you enroll with Actelion Pathways®, you will get a call to walk through the process and discuss medicine delivery. Here are the basic steps you will need to take to fill your UPTRAVI® (selexipag) prescription.

Steps to the specialty pharmacy process

  • Learn about specialty pharmacies.

    Certain medicines, such as UPTRAVI, aren’t kept at your local pharmacy. Instead, a specialty pharmacy will ship UPTRAVI directly to your home.

  • Connect with a specialty pharmacy.

    Either CVS Specialty or Accredo specialty pharmacy will call you to discuss financial responsibilities and shipment information.

    You or your healthcare provider may have chosen additional support services such as an in-home nurse visit. Your specialty pharmacy will help you to schedule this.

  • Finding the dose that is right for you.

    It can take time for your body to adjust to UPTRAVI. You may experience side effects as part of the process of finding the dose that is right for you. This is expected and more likely to occur when starting UPTRAVI or when your healthcare provider changes your dose.

  • Once your dose is found, continue on your treatment.

    Each month, the specialty pharmacy will call you to confirm details of the delivery and to arrange your refill.

Calls may come from a number you do not recognize. If you miss the call, try to call back as soon as possible to make sure your UPTRAVI shipment is not delayed.

Need additional assistance?

Your Actelion Pathways Case Manager can also help coordinate with your doctor, insurance company, and specialty pharmacy to find out if you have coverage for your medicine, and explore financial assistance options or additional information if needed.

Next: Still have more questions? Find additional information in Patient Resources

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IMPORTANT SAFETY INFORMATION

What is the most important information about UPTRAVI?

Who should not take UPTRAVI?

  • Do not take UPTRAVI if you take gemfibrozil because this medicine may affect how UPTRAVI works and cause side effects

What should I tell my doctor before taking UPTRAVI?

Tell your doctor if you:

  • Have liver problems
  • Have narrowing of the pulmonary veins (veins in your lungs). This is called pulmonary veno-occlusive disease (PVOD)
  • Are pregnant or plan to become pregnant. It is not known if UPTRAVI will harm your unborn baby
  • Are breastfeeding or plan to breastfeed. It is not known if UPTRAVI passes into your breast milk. You and your doctor should decide if you will take UPTRAVI or breastfeed. You should not do both.
  • Have any other medical conditions
  • Are taking any other prescription or over-the-counter medicines, vitamins, or herbal supplements
See More

What is UPTRAVI?

UPTRAVI (selexipag) is a prescription medicine used to treat pulmonary arterial hypertension (PAH, WHO Group 1), which is high blood pressure in the arteries of your lungs.

IMPORTANT SAFETY INFORMATION

What is the most important information about UPTRAVI?

Who should not take UPTRAVI?

  • Do not take UPTRAVI if you take gemfibrozil because this medicine may affect how UPTRAVI works and cause side effects

What should I tell my doctor before taking UPTRAVI?

Tell your doctor if you:

  • Have liver problems
  • Have narrowing of the pulmonary veins (veins in your lungs). This is called pulmonary veno-occlusive disease (PVOD)
  • Are pregnant or plan to become pregnant. It is not known if UPTRAVI will harm your unborn baby
  • Are breastfeeding or plan to breastfeed. It is not known if UPTRAVI passes into your breast milk. You and your doctor should decide if you will take UPTRAVI or breastfeed. You should not do both.
  • Have any other medical conditions
  • Are taking any other prescription or over-the-counter medicines, vitamins, or herbal supplements
See More

What is UPTRAVI?

UPTRAVI (selexipag) is a prescription medicine used to treat pulmonary arterial hypertension (PAH, WHO Group 1), which is high blood pressure in the arteries of your lungs.

UPTRAVI can help delay (slow down) the progression of your disease and lower your risk of being hospitalized for PAH.

It is not known if UPTRAVI is safe and effective in children.


What are the possible side effects of UPTRAVI?

The most common side effects are:

  • Headache
  • Diarrhea
  • Jaw pain
  • Nausea
  • Muscle pain
  • Vomiting
  • Pain in arms or legs
  • Temporary reddening of the skin (flushing)
  • Joint pain
  • Low red blood cell count
  • Less appetite than usual
  • Rash

Talk to your doctor if you have a side effect that bothers you or does not go away. These are not all the possible side effects of UPTRAVI. For more information, ask your doctor or pharmacist.

You may report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Keep UPTRAVI and all other medicines away from children.

What other medicines might interact with UPTRAVI?

  • UPTRAVI and other medicines may affect each other, causing side effects. Tell your doctor about all the medicines you are taking. Do not start any new medicine until you check with your doctor

How should I take UPTRAVI?

  • Take UPTRAVI exactly as your doctor tells you to take it. Usually, your doctor will have you take UPTRAVI twice a day. Taking UPTRAVI with food may help you tolerate UPTRAVI better
  • Swallow UPTRAVI tablets whole. Do not split, crush, or chew tablets
  • Tell your doctor if you have any form of liver disease. Your doctor may need to change your dose of UPTRAVI
  • UPTRAVI is measured in micrograms (mcg). Tablets come in the following strengths: 200, 400, 600, 800, 1000, 1200, 1400, and 1600 mcg

Please see full Prescribing Information and Patient Product Information for UPTRAVI.